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Hello!
New Alert: VolitionRx Limited (NYSE American: VNRX)
VNRX is our new NYSE American biotech alert.
This is a hidden gem opportunity that not many have seen – and we are amongst the first to bring it to your attention.
The chart setup alone is pointing to a massive breakout opportunity.
This means that momentum can build very quickly.
And it is still trading for just around 2.00.
VNRX is a NYSE American listed “multi-national epigenetics company” that is “developing and commercializing simple, easy to use, cost-effective blood tests to help detect and monitor a range of diseases, including some cancers and diseases associated with NETosis, such as sepsis”.
Epigenetic changes can be detected before the diseased cells themselves become abnormal enough to show up in traditional biopsies, and oftentimes before the first symptoms are felt.
VNRX is “dedicated to saving lives and improving outcomes for people and animals with life-altering diseases through earlier detection, disease and treatment monitoring”.
The company’s “patented Nucleosomics™ technology” “detects characteristic epigenetic changes in nucleosomes that occur from the earliest stages of disease enabling early detection and potentially a better way to monitor disease progression and a patient’s response to treatment”.
Based on this core, “cutting-edge technology” VNRX has “developed a portfolio of Nu.Q® assays which are simple, low-cost, accessible, routine blood tests”.
Early detection and monitoring have the potential to not only prolong the life of patients, but also to improve their quality of life.
Here is a number that puts everything else in context:
Sadly, cancer is "a leading cause of death worldwide, accounting for nearly 10 million deaths in 2022."
The single most powerful determinant of whether a patient survives is how early it is caught.
Stage I survival rates for most cancers exceed 90%.
By Stage IV, many of those same cancers drop below 20%.
The problem has always been detection.
Tumors are often invisible to standard diagnostics until they have already spread.
VNRX is working to change that with a simple blood test.
And on March 18, 2026 they released data that stopped us in our tracks:
“Volition Reports Breakthrough in Liquid Biopsy: Achievement of over 99% Purity in Isolating Cancer DNA”
“Targets $36 Billion TAM in Early Cancer Detection and MRD.”
“Company in active discussions with global diagnostic leaders to accelerate commercialization.”
But that’s not all, on March 25, 2026 the company followed-up with another announcement:
“Volition Announces Detection of Over 95% of Early-Stage Cancers”
This could be a ground floor opportunity that wall street has not yet discovered.
As the company further explains:
“The biggest problem facing liquid biopsy worldwide is that the vast majority of circulating DNA in blood plasma samples comes from healthy cells, not cancer cells.”
“In a world first new technology, Volition has overcome this hurdle and produced >99% pure cancer derived plasma DNA sequence sets for liquid biopsy.”
Dr Jake Micallef, Chief Scientific Officer, Volition commented:
"Removal of background normal cell free DNA from the blood to reveal this level of tumor derived DNA has been a long term goal of liquid biopsy. I believe this is a world-first and could, in my opinion, represent the biggest scientific breakthrough in cancer testing and monitoring in recent years.
Furthermore:
"These methodological and technological breakthroughs represent a novel liquid biopsy method for a novel class of potentially thousands of liquid biopsy sequence biomarkers”.
VNRX calls this “technology "Capture-Seq™" and it shows potential for both a multi-cancer early detection (MCED) approach, either alone or in combination with other tests, and the detection of Minimal Residual Disease”.
Mr. Gael Forterre, Chief Commercial Officer, Volition added:
"This scientific breakthrough has generated a lot of interest with potential licensing partners.”
In the subsequent March 25, 2026 press release VNRX released “the data from a blinded validation cohort of 81 subjects (colorectal and lung cancer patients = 59, healthy controls = 22) and are extremely encouraged by the results, particularly in early-stage cancer detection”.
“Details are summarized in the table below:
Cancer Stage Detection Rate
I 94% (17/18)
II 96% (26/27)
III 100% (2/2)
IV 91% (10/11)”
The company believes “this technology could, with further development, become very widely used, in both the human and veterinary markets, and fits very well with our Nu.Q® product portfolio”.
Capture-Seq is the emerging breakthrough - but it sits on top of a platform that is already generating real revenue and real clinical traction across multiple product lines:
Nu.Q Vet Cancer Test is an “accessible and affordable screening test to aid in the early detection of cancer in dogs”.
Nu.Q NETs assay is a “groundbreaking CE-marked diagnostic solution that clinicians can use to detect NETosis”.
Nu.Q® Discover is an “invaluable research tool for R&D professionals working within the field of Pharmacoepigenetics, studying the epigenetic basis for variation in response to drugs”.
Nu.Q® Cancer “encapsulates a range of simple, cost effective blood-based assays”
The company has announced multiple accomplishments recently.
In December, VNRX “announced the inclusion of our Nu.Q® NETs assay in a real-world interventional evaluation of early detection of sepsis, in a government-backed (~$7.3 million) program in France”.
In Q4 2025, VNRX received its “first order for the Nu.Q® Cancer assays for clinical certification ahead of routine clinical use in lung cancer”.
Furthermore, in March 2026, the company announced “First Ever Automated Nu.Q® Vet Cancer Test with Fujifilm Vet Systems”
As the company further explained in this press release:
"Since our launch of the Nu.Q® Vet Cancer Test in July 2024, there has been an incredible amount of interest amongst Japanese veterinarians, indeed the number of veterinary hospitals registered to use the test in Japan already exceeds 1,700.
"This automated test will enable a more rapid turnaround and high throughput to meet increasing demand."
In addition, the company also announced:
“VolitionRx Secures EUR 2.0 Million of Non-Dilutive Funding from Regional Government Agencies in Belgium”
“Volition will use the proceeds from the financing for ongoing development of its Nu.Q® product portfolio, including taking forward its regulatory transition program for Nu.Q® NETs (from IVDD to IVDR), the continued research and development of a Lateral Flow product, specifically to enable access to its Nu.Q® NETs product in Low Income Countries and more.”
For “Full Fiscal Year 2025 Financial Results” VNRX stated:
“Finished the year strongly with year over year revenue growth for Q4 of 133%.”
“Full-year revenue for 2025 was $1.7 million, representing growth of 40% over the previous year.”
In April, the company announced:
“Volition Launches rNuQ™ Webshop Broadening Product Range”
Dr Jasmine Kway, Chief Executive Officer, Singapore Volition commented:
"This is a further expansion of our Nu.Q® Discover pillar, where we are now serving close to 100 clients worldwide, including many top pharma and diagnostic companies, accelerating disease research and drug development across multiple therapeutic areas. Some of these pharmaceutical companies have progressed to late stage clinical trials using our assays as pharmacodynamic biomarkers.”
Two weeks ago, the company announced:
“Volition Announces Breakthrough Finger-Prick Detection of Nucleosomes; Expanding Global Market Potential for Sepsis Testing”
“Results showed the feasibility of early detection of immune disruptions that can occur in a range of conditions including sepsis, simply and rapidly when using the test in a variety of settings (doctor's office, Emergency Department, Intensive Care Unit setting, or home self-test), without the need to send a blood sample to a hospital laboratory for testing.”
Unfortunately, “1 in 5 deaths worldwide are associated with sepsis”, the “body’s overactive and toxic response to an infection”.
It is the “number 1 cause of death in hospitals” and contributes to a healthcare cost of “$62bn pa in USA alone”.
Mr. Cameron Reynolds, Chief Executive Officer, Volition said:
"The ability to rapidly identify high-risk patients at the Point-of-Care by quantifying their nucleosome levels using a finger-prick sample and simple lateral flow device could enable quicker clinical decision making and consequently better patient outcomes.
"This is a potential gamechanger, not only in diseases where time is critical such as sepsis, but also in significantly expanding potential use cases beyond traditional hospital infrastructure. It also creates a compelling pathway into underserved low-income countries, where laboratory infrastructure may be weak or non-existent."
In addition, last week, the company announced:
“VolitionRx Announces Submission of Manuscript for Nu.Q® Vet Cancer Test in Cats”
“The publication of this study in a peer reviewed journal is expected subsequently to unlock a $5 million contractual milestone payment”
The Nu.Q® Vet Feline Test taps into a significant, rapidly growing market: “There are approximately 73.8 million pet cats in the United States alone.”
Yesterday, the company announced:
“VolitionRx Limited Schedules First Quarter 2026 Earnings Conference Call and Business Update”
“Conference call to take place on Friday, May 15 at 8:30 a.m. U.S Eastern Time”
We believe VNRX could be positioned for significant upside.
Make sure to do your own due diligence.
Sources: S, WHO, Cancer, Presentation, PR1, PR2, PR3, PR4, PR5, PR6, PR7, PR8, PR9, PR10, PR11, PR12, PR13, Website, Chart
Happy Trading!
SmallCapStocks Team
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